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Clinical Manifestation and Management of Dengue Viral Infection in Children's Ward RSVP Prof DR RD Kandou

Rampengan, Novie Homenta and Limantoro, Andrew and Sanusi, Holly Setiawati and Tatura, Suryadi and Rampengan, T. H. and Ottay, Ronald Immanuel (2017) Clinical Manifestation and Management of Dengue Viral Infection in Children's Ward RSVP Prof DR RD Kandou. In: 11th International Congress of Tropical Pediatris ICTP 2017, 4-11 Agustus 2017, Yogyakarta.

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      Abstract

      Background : Dengue viral infection is still a health problem in Indonesia. Dengue virus infection comes in 3 stages of clinical manifestation and management : Dengue Fever(DF), Dengue Hemorhagic Fever (DHF) and Dengue Shock Syndrome (DSS). Each stages has different clinical manifestation. Material: The subjects of the study were the patients treated in the pediatric Tropical Division of RSVP Prof. Kandou from January 2014 to December 2016 with diagnosis of DFI DHFI DSS caused by Dengue viral infection based on the WHO 1997 criteria and performed serology test. Results: The prominent clinical manifestation of 123 subjects were fever 100% of DF, 100% of DHF and 100% of DSS. Vomiting 50.1% in DF, 61.5% in DHF and 58% in DSS, abdominal pain 50.4% in DF, 68% in DHF and 40.1% in DSS, rash 47.1% in DF, 65.3% in DHF and 82% in DSS, dizziness 19% in DF, 11% in DHF and 15% in DSS, bleeding gums 6.5% in DF, 7.2% in DHF and 14.5% in DSS, epistaxis 4.1% in all cases, and melena 3.2% in DF, 4.1% in DHF and 5.5% in DSS. In physical examination, we found positive tourniquet test 50.4% in DF, 70,5% in DHF and 65.1 % in DSS. Laboratory results showed lower mean leukocyte rates in DSS compared with DD and DBD, trombocytopeni in greater level in DHF and more in DSS and were statistically significantly different (p = 0.007). NS-I Positive in 89% ofDF, 85% in DHF and 73%in DSS. The IgG and Ig M positive in 80.3% of DF, 95.5% in DHF and 98.6% in DSS. The use of crystalloid fluid in DF was 81.1 %, DHF 86.4% and DSS 100% of all cases, while the use of colloidal fluid in DSS was 56.1 %. Conclusion : The significant clinical symptoms included fever, nausea, vomiting, abdominal pain, epistaxis, and melena. The dominant physical examination were positive in tourniquet test. Leukopenia and tromocytopeni were more common in DF and DSS than DD. The Nsl test more dominant in DS than DHF and DSS. IgG and IgM anti dengue dominant in DHF and DSS.

      Item Type: Conference or Workshop Item (Poster)
      Subjects: R Medicine > R Medicine (General)
      R Medicine > RJ Pediatrics
      Divisions: Fakultas Kedokteran > Fakultas Kedokteran Umum
      Depositing User: Mr. Benhard W. Tampangela, ST
      Date Deposited: 07 Sep 2017 10:21
      Last Modified: 07 Sep 2017 10:21
      URI: http://repo.unsrat.ac.id/id/eprint/1693

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